INT334211

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Context Info
Confidence 0.32
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 3.03
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell death (TARDBP) mRNA processing (TARDBP) nucleolus (TARDBP)
RNA binding (TARDBP) nucleus (TARDBP) DNA binding (TARDBP)
Anatomy Link Frequency
brain 2
TARDBP (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 9 5.00 Very Low Very Low Very Low
Eae 3 5.00 Very Low Very Low Very Low
headache 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Frontotemporal Lobar Degeneration 24 99.68 Very High Very High Very High
Dementia 102 98.28 Very High Very High Very High
Disease 207 92.12 High High
Creutzfeldt Jakob Disease 6 89.96 High High
Neurodegenerative Disease 42 62.16 Quite High
Vascular Dementia 12 59.40 Quite High
Parkinson's Disease 15 9.92 Low Low
Cognitive Disorder 75 5.00 Very Low Very Low Very Low
Stress 9 5.00 Very Low Very Low Very Low
INFLAMMATION 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In line with the reported increased gene expression of TDP-43 in brain tissues [69], elevated 45?
Positive_regulation (increased) of Gene_expression (expression) of TDP-43 in brain
1) Confidence 0.32 Published 2010 Journal International Journal of Alzheimer's Disease Section Body Doc Link PMC2945639 Disease Relevance 1.06 Pain Relevance 0
With respect to FTLD, cNEUPRO found elevated mean levels of the TAR DNA-binding Protein 43 (TDP-43) and reduced A?
Positive_regulation (elevated) of Gene_expression (levels) of TAR DNA-binding Protein 43 associated with frontotemporal lobar degeneration
2) Confidence 0.23 Published 2010 Journal International Journal of Alzheimer's Disease Section Body Doc Link PMC2945639 Disease Relevance 0.99 Pain Relevance 0
With respect to FTLD, cNEUPRO found elevated mean levels of the TAR DNA-binding Protein 43 (TDP-43) and reduced A?
Positive_regulation (elevated) of Gene_expression (levels) of TDP-43 associated with frontotemporal lobar degeneration
3) Confidence 0.23 Published 2010 Journal International Journal of Alzheimer's Disease Section Body Doc Link PMC2945639 Disease Relevance 0.99 Pain Relevance 0

General Comments

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