INT334266

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Context Info
Confidence 0.35
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.16
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Irak1, Myd88) signal transduction (Irak1, Myd88) intracellular (Myd88)
protein complex (Myd88) cytosol (Myd88) nucleus (Irak1)
Irak1 (Mus musculus)
Myd88 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 34 93.04 High High
Inflammation 62 36.28 Quite Low
Paracetamol 4 23.32 Low Low
fibrosis 8 5.00 Very Low Very Low Very Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
rheumatoid arthritis 5 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 84 81.12 Quite High
Necrosis 4 80.64 Quite High
Liver Disease 8 42.48 Quite Low
INFLAMMATION 62 36.28 Quite Low
Autoimmune Disease 23 33.68 Quite Low
Hepatocellular Cancer 94 31.52 Quite Low
Hepatitis 14 22.32 Low Low
Hepatitis B Virus Infection 16 21.44 Low Low
Hepatitis C Virus Infection 16 21.04 Low Low
Alcoholic Liver Diseases 4 20.64 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Likewise, the splice variant IRAK1c acts in a similar manner by interacting with MyD88 and IRAK4.
IRAK1c Binding (interacting) of MyD88
1) Confidence 0.35 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2945668 Disease Relevance 0.16 Pain Relevance 0.09
In the MyD88-dependent pathway, MyD88 is associated with IRAK4, IRAK1, and/or IRAK2.
IRAK1 Binding (associated) of MyD88-dependent
2) Confidence 0.23 Published 2010 Journal Gastroenterology Research and Practice Section Body Doc Link PMC2995932 Disease Relevance 0 Pain Relevance 0
In the MyD88-dependent pathway, MyD88 is associated with IRAK4, IRAK1, and/or IRAK2.
IRAK1 Binding (associated) of MyD88
3) Confidence 0.23 Published 2010 Journal Gastroenterology Research and Practice Section Body Doc Link PMC2995932 Disease Relevance 0 Pain Relevance 0

General Comments

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