INT3343

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Context Info
Confidence 0.62
First Reported 1978
Last Reported 2010
Negated 5
Speculated 3
Reported most in Body
Documents 24
Total Number 27
Disease Relevance 11.18
Pain Relevance 1.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (PTH) extracellular region (PTH) cell-cell signaling (PTH)
Anatomy Link Frequency
parathyroid 3
blood 2
parathyroid glands 1
plasma 1
endochondral bone 1
PTH (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 1 99.24 Very High Very High Very High
psoriasis 9 96.52 Very High Very High Very High
Pain 28 96.20 Very High Very High Very High
anticonvulsant 2 87.60 High High
headache 16 86.84 High High
backache 3 83.16 Quite High
alcohol 1 83.12 Quite High
positron emission tomography 1 81.84 Quite High
addiction 1 80.40 Quite High
anesthesia 1 77.84 Quite High
Disease Link Frequency Relevance Heat
Chronic Renal Failure 18 99.56 Very High Very High Very High
Obesity 13 99.20 Very High Very High Very High
Osteoporosis 319 99.08 Very High Very High Very High
Hypercalcemia 188 98.52 Very High Very High Very High
Muscle Weakness 6 97.24 Very High Very High Very High
Stress Fractures 36 97.20 Very High Very High Very High
Psoriasis 11 97.00 Very High Very High Very High
Kidney Stones 29 96.52 Very High Very High Very High
Pain 29 96.20 Very High Very High Very High
Congenital Anomalies 12 94.28 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is possible that physical activity associated with BCT had an interactive effect on vitamin D and PTH levels, as others have described complex relationships between physical activity, vitamin D status, PTH levels, and bone health [18,19].
Spec (possible) Regulation (effect) of PTH
1) Confidence 0.62 Published 2010 Journal J Int Soc Sports Nutr Section Body Doc Link PMC3017021 Disease Relevance 0 Pain Relevance 0
Since then it has been established that the kidneys play a major role in the regulation of calcium, phosphate, and parathyroid hormone, and that chronic renal failure is characterized by profound alterations in the normal metabolic homeostasis of the human body.
Regulation (regulation) of parathyroid hormone in body associated with chronic renal failure
2) Confidence 0.62 Published 1984 Journal J. Pediatr. Surg. Section Abstract Doc Link 6481583 Disease Relevance 0.74 Pain Relevance 0
Sequential changes in plasma intact and whole parathyroid hormone levels during parathyroidectomy for secondary hyperparathyroidism.
Regulation (changes) of parathyroid hormone in plasma associated with hypercalcemia
3) Confidence 0.60 Published 2005 Journal World J Surg Section Title Doc Link 15650804 Disease Relevance 0.35 Pain Relevance 0.08
There is no demonstrable additive or synergistic effect between alendronate and PTH therapy when used together.


Neg (no) Regulation (effect) of PTH
4) Confidence 0.44 Published 2007 Journal Clinical Interventions in Aging Section Body Doc Link PMC2686338 Disease Relevance 0.07 Pain Relevance 0
This blunting of response to PTH therapy following BPS treatment may have to do with the avidity of BPS binding to hydroxyapatite in osteoclasts, which varies by BPS type.
Regulation (response) of PTH in osteoclasts
5) Confidence 0.42 Published 2010 Journal International Journal of Women's Health Section Body Doc Link PMC2971740 Disease Relevance 0.16 Pain Relevance 0
Ethnicity did not affect BCT-induced changes in PTH.
Regulation (changes) of PTH
6) Confidence 0.39 Published 2010 Journal J Int Soc Sports Nutr Section Abstract Doc Link PMC3017021 Disease Relevance 0.12 Pain Relevance 0
In the AES guideline, one single serum PTH measurement is recommended at 4?
Regulation (recommended) of serum PTH
7) Confidence 0.39 Published 2010 Journal Journal of Oncology Section Body Doc Link PMC2926682 Disease Relevance 0.52 Pain Relevance 0
The objective of this pilot study was to investigate the effects of military training on vitamin D status and PTH, an indirect vitamin D status indicator, in female military personnel [8].
Spec (investigate) Regulation (effects) of PTH
8) Confidence 0.27 Published 2010 Journal J Int Soc Sports Nutr Section Body Doc Link PMC3017021 Disease Relevance 0.71 Pain Relevance 0
This finding is consistent with other studies in normal subjects where intake of oral alkaline [28] and magnesium [30] loads do not alter PTH levels in the short term.
Neg (not) Regulation (alter) of PTH
9) Confidence 0.27 Published 2010 Journal BMC Res Notes Section Body Doc Link PMC2908636 Disease Relevance 0 Pain Relevance 0
Two randomized, placebo-controlled studies with PTH were done in men with osteoporosis.
Regulation (controlled) of PTH associated with osteoporosis
10) Confidence 0.27 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC193734 Disease Relevance 0.71 Pain Relevance 0.17
The NNT was 71 (42 to 422) in patients without a baseline fracture, and 22 (11 to 422) in those with a baseline fracture.18 Recently, in a reanalysis of the TOP trial data, the efficacy of PTH in the prevention of a new fracture was demonstrated to be greater in patients with a low lumbar BMD (T-score < ?
Regulation (efficacy) of PTH
11) Confidence 0.27 Published 2010 Journal International Journal of Women's Health Section Body Doc Link PMC2971708 Disease Relevance 0.05 Pain Relevance 0
Skewed variables were transformed and re-evaluated for normality: the ferritin level was transformed by the log10 function and the intact PTH and aluminium values were transformed by the natural logarithm function.
Regulation (values) of PTH
12) Confidence 0.26 Published 2008 Journal Nephrology Dialysis Transplantation Section Body Doc Link PMC2517147 Disease Relevance 0.08 Pain Relevance 0
Serum and urine phosphate levels, alkaline phosphatase and parathyroid hormone values were within normal ranges.
Regulation (values) of parathyroid hormone in parathyroid
13) Confidence 0.26 Published 1978 Journal Clin. Orthop. Relat. Res. Section Abstract Doc Link 709936 Disease Relevance 0.35 Pain Relevance 0.08
The mechanism described operates still more intensively under the effects of parathyroid hormone, aldosterone, and enkephalin, the blood levels of which are elevated in patients with SPs.
Regulation (effects) of parathyroid hormone in blood associated with psoriasis and enkephalin
14) Confidence 0.26 Published 2009 Journal Med. Hypotheses Section Abstract Doc Link 18926642 Disease Relevance 1.14 Pain Relevance 0.53
His serum intact PTH value was 1,600 pg/ml with elevated ALP (387 IU/l) and osteocalcin (400 ng/ml).
Regulation (value) of PTH
15) Confidence 0.26 Published 2004 Journal Clin. Nephrol. Section Abstract Doc Link 14964461 Disease Relevance 0.34 Pain Relevance 0.10
Figure 4 shows the change of serum Calcium and PTH levels during patient's hospitalization
Regulation (change) of PTH
16) Confidence 0.25 Published 2005 Journal World J Surg Oncol Section Body Doc Link PMC1187928 Disease Relevance 1.39 Pain Relevance 0.08
Roe and Arnaud and colleagues performed an randomized, controlled trial of PTH (1–34) at 40 ?
Regulation (controlled) of PTH
17) Confidence 0.24 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC193734 Disease Relevance 0.09 Pain Relevance 0
The efficacy of PTH (1-84) in the prevention of new vertebral fractures in women with or without a prevalent fracture at baseline was demonstrated in the TOP study.
Regulation (efficacy) of PTH
18) Confidence 0.24 Published 2010 Journal International Journal of Women's Health Section Body Doc Link PMC2971708 Disease Relevance 0.24 Pain Relevance 0
Two studies were published concurrently in 2003 examining the effect of alendronate on PTH; one in postmenopausal women and one in elderly men with low bone density.
Spec (examining) Regulation (effect) of PTH
19) Confidence 0.23 Published 2007 Journal Clinical Interventions in Aging Section Body Doc Link PMC2686338 Disease Relevance 0.45 Pain Relevance 0
There were no significant differences in PTH levels after 24 hours or 28 days of verapamil treatment.
Neg (no) Regulation (differences) of PTH
20) Confidence 0.23 Published 1995 Journal Clin. Endocrinol. (Oxf) Section Body Doc Link 7889637 Disease Relevance 0.27 Pain Relevance 0

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