INT334358

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Context Info
Confidence 0.17
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.98
Pain Relevance 0.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Ephb1) signal transduction (Ephb1) plasma membrane (Ephb1)
cytoplasm (Ephb1)
Rvm (Mus musculus)
Ephb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Rostral ventromedial medulla 77 100.00 Very High Very High Very High
parabrachial 2 98.40 Very High Very High Very High
Dorsal horn 9 93.96 High High
projection neuron 7 89.20 High High
Hyperalgesia 10 68.88 Quite High
Peripheral nerve injury 1 60.88 Quite High
Neuropathic pain 16 52.68 Quite High
Inflammation 9 37.92 Quite Low
nMDA receptor 1 33.28 Quite Low
nMDA receptor antagonist 1 24.56 Low Low
Disease Link Frequency Relevance Heat
Nervous System Injury 53 99.08 Very High Very High Very High
Urological Neuroanatomy 4 80.32 Quite High
Neuropathic Pain 19 75.32 Quite High
Nociception 4 73.92 Quite High
Hypersensitivity 7 71.00 Quite High
Hyperalgesia 11 68.88 Quite High
Injury 4 50.00 Quite Low
INFLAMMATION 9 37.92 Quite Low
Pain 15 5.00 Very Low Very Low Very Low
Amputation 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore the absence of ERK activation within the RVM of neonates following SNI surgery is unlikely to be explained by the developmental state of ascending pathways.
RVM Positive_regulation (activation) of ERK associated with nervous system injury and rostral ventromedial medulla
1) Confidence 0.17 Published 2010 Journal Mol Pain Section Body Doc Link PMC2945971 Disease Relevance 0.98 Pain Relevance 0.82

General Comments

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