INT334419

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Context Info
Confidence 0.73
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 2.84
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (SPINK1)
SPINK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 5 91.72 High High
Inflammation 12 84.08 Quite High
abdominal pain 7 5.00 Very Low Very Low Very Low
palliative 4 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
nud 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatitis 50 99.92 Very High Very High Very High
Rectal Cancer 36 99.20 Very High Very High Very High
Disease 101 97.32 Very High Very High Very High
Colon Cancer 136 92.56 High High
Cancer 120 87.28 High High
Malignant Neoplastic Disease 12 86.96 High High
INFLAMMATION 12 84.08 Quite High
Renal Cancer 16 75.28 Quite High
Metastasis 36 60.68 Quite High
Reprotox - General 1 4 19.76 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To date, only a few cases have demonstrated that pancreatitis is caused by simultaneous CFTR and SPINK1 mutations (5.5%), of PRSS1 and SPINK1 (1.3%), and of PRSS1 and CFTR (1.8%).
Localization (caused) of SPINK1 associated with pancreatitis
1) Confidence 0.73 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2970583 Disease Relevance 0.49 Pain Relevance 0.09
Correlation between s-TATI and t-TATI
Localization (Correlation) of s-TATI
2) Confidence 0.57 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2946315 Disease Relevance 0.35 Pain Relevance 0
Notably, the independent prognostic value of s-TATI remained significant for both DFS and OS when adjusted for age in the multivariate Cox regression analysis.
Localization (value) of s-TATI
3) Confidence 0.57 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2946315 Disease Relevance 0.97 Pain Relevance 0.04
Correlation between s-TATI and t-TATI
Localization (Correlation) of t-TATI
4) Confidence 0.57 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2946315 Disease Relevance 0.35 Pain Relevance 0
Correlations between s-TATI and clinicopathological characteristics
Localization (Correlations) of s-TATI
5) Confidence 0.57 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2946315 Disease Relevance 0.67 Pain Relevance 0

General Comments

This test has worked.

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