INT334471

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Arhgdia, Cdc42ep3) cytoskeleton (Cdc42ep3) biological_process (Cdc42ep3)
Arhgdia (Mus musculus)
Cdc42ep3 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 4 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Mevalonate Kinase Deficiency 58 47.44 Quite Low
Fever 5 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Syndrome 3 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Hypergammaglobulinemia 1 5.00 Very Low Very Low Very Low
Dementia 1 5.00 Very Low Very Low Very Low
Frailty 1 5.00 Very Low Very Low Very Low
Headache 1 5.00 Very Low Very Low Very Low
Ataxia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because the isoprenyl moiety plays a critical role in interaction with Rho-GDI (Bustelo et al 2007), nonisoprenylated GTPases will no longer be inhibited by Rho-GDI and, consequently, intrinsic nucleotide exchange, i.e., GDP release and GTP binding, may occur.
Rho-GDI Negative_regulation (inhibited) of GTPases
1) Confidence 0.00 Published 2010 Journal J Inherit Metab Dis Section Body Doc Link PMC2946549 Disease Relevance 0 Pain Relevance 0

General Comments

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