INT334500

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.47
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (SPARCL1) extracellular space (SPARCL1) extracellular region (SPARCL1)
proteinaceous extracellular matrix (SPARCL1)
Anatomy Link Frequency
basophils 1
mast cells 1
IGHE (Homo sapiens)
SPARCL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 28 96.92 Very High Very High Very High
Inflammation 30 81.76 Quite High
tolerance 2 57.64 Quite High
corticosteroid 12 48.36 Quite Low
agonist 14 35.44 Quite Low
antagonist 8 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
pruritus 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 28 81.76 Quite High
Respiratory Disease 6 80.52 Quite High
Hypersensitivity 56 79.68 Quite High
Asthma 100 65.80 Quite High
Disease 22 63.12 Quite High
Airway Remodeling 4 52.28 Quite High
Adhesions 4 52.00 Quite High
Rhinitis 18 5.00 Very Low Very Low Very Low
Anaphylaxis 6 5.00 Very Low Very Low Very Low
General Immunology 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Once IgE is produced, it binds to mast cells and basophils where cross-linking of high affinity IgE receptors bound by IgE and antigen leads to mediator and cytokine release.
IgE Binding (binds) of mast in basophils associated with cytokine
1) Confidence 0.01 Published 2010 Journal Allergy, Asthma & Immunology Research Section Body Doc Link PMC2946700 Disease Relevance 0.73 Pain Relevance 0.27
Once IgE is produced, it binds to mast cells and basophils where cross-linking of high affinity IgE receptors bound by IgE and antigen leads to mediator and cytokine release.
IgE Binding (binds) of mast in mast cells associated with cytokine
2) Confidence 0.00 Published 2010 Journal Allergy, Asthma & Immunology Research Section Body Doc Link PMC2946700 Disease Relevance 0.73 Pain Relevance 0.27

General Comments

This test has worked.

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