INT334510

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Context Info
Confidence 0.30
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.40
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (CCR3) extracellular space (CCR3) cell adhesion (CCR3)
plasma membrane (CCR3) signal transducer activity (CCR3)
CCR3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 30 99.92 Very High Very High Very High
cytokine 28 45.32 Quite Low
agonist 14 5.00 Very Low Very Low Very Low
corticosteroid 12 5.00 Very Low Very Low Very Low
antagonist 8 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
pruritus 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 28 99.92 Very High Very High Very High
Hypersensitivity 56 99.66 Very High Very High Very High
Asthma 100 89.92 High High
Eosinophilia 2 61.80 Quite High
Adhesions 4 11.52 Low Low
Disease 22 5.00 Very Low Very Low Very Low
Rhinitis 18 5.00 Very Low Very Low Very Low
Respiratory Disease 6 5.00 Very Low Very Low Very Low
Anaphylaxis 6 5.00 Very Low Very Low Very Low
General Immunology 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It contains two modified phosphorothioate anti-sense oligonucleotides designed to inhibit allergic inflammation by down-regulating human CCR3 and the common beta-chain of IL-3, IL-5 and GM CSF.
Negative_regulation (down) of CCR3 associated with inflammation and hypersensitivity
1) Confidence 0.30 Published 2010 Journal Allergy, Asthma & Immunology Research Section Body Doc Link PMC2946700 Disease Relevance 0.70 Pain Relevance 0.05
It contains two modified phosphorothioate anti-sense oligonucleotides designed to inhibit allergic inflammation by down-regulating human CCR3 and the common beta-chain of IL-3, IL-5 and GM CSF.
Negative_regulation (regulating) of CCR3 associated with inflammation and hypersensitivity
2) Confidence 0.30 Published 2010 Journal Allergy, Asthma & Immunology Research Section Body Doc Link PMC2946700 Disease Relevance 0.70 Pain Relevance 0.05

General Comments

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