INT334524

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.61
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Sema3a) extracellular region (Sema3a) nucleus (Foxq1)
embryo development (Foxq1) DNA binding (Foxq1) transcription factor binding (Foxq1)
Anatomy Link Frequency
nerve 1
Sema3a (Mus musculus)
Foxq1 (Mus musculus)
Pain Link Frequency Relevance Heat
Nerve growth factor 49 100.00 Very High Very High Very High
Inflammation 7 67.92 Quite High
substance P 8 5.00 Very Low Very Low Very Low
qutenza 3 5.00 Very Low Very Low Very Low
c fibre 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Antihistamine 2 5.00 Very Low Very Low Very Low
Peripheral nervous system 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Neuropeptide 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pruritus 24 99.46 Very High Very High Very High
Eczema 108 99.20 Very High Very High Very High
Congenital Anomalies 4 94.16 High High
Hypersensitivity 4 91.88 High High
Skin Diseases 3 68.44 Quite High
INFLAMMATION 5 67.92 Quite High
Disease 4 5.00 Very Low Very Low Very Low
Erythema 3 5.00 Very Low Very Low Very Low
Papular Skin Disease 2 5.00 Very Low Very Low Very Low
Acanthosis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In this paper, we would like to review the recent papers concerning the pathogenesis and biomarker of AD and its itch and to discuss a probable role of SA, interleukin-18 (IL-18), nerve growth factor (NGF) and semaphorin 3A (Sema3A) of an axon guidance molecule in pathogenesis and treatment of AD.


semaphorin 3A Spec (probable) Regulation (role) of SA in nerve associated with nerve growth factor, pruritus and eczema
1) Confidence 0.04 Published 2010 Journal Allergy, Asthma & Immunology Research Section Body Doc Link PMC2946701 Disease Relevance 1.61 Pain Relevance 0.13

General Comments

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