INT334527

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Context Info
Confidence 0.15
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.48
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Sema3a, Il4) cell differentiation (Sema3a) extracellular space (Il4)
Anatomy Link Frequency
dendritic cells 1
T cells 1
Sema3a (Mus musculus)
Il4 (Mus musculus)
Pain Link Frequency Relevance Heat
Nerve growth factor 49 89.44 High High
Antinociceptive 1 49.40 Quite Low
Pain 1 38.76 Quite Low
qutenza 3 32.92 Quite Low
vanilloid receptor subtype 1 1 21.64 Low Low
Inflammation 7 18.20 Low Low
substance P 8 5.00 Very Low Very Low Very Low
c fibre 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Antihistamine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Eczema 108 99.32 Very High Very High Very High
Acanthosis 2 98.32 Very High Very High Very High
Congenital Anomalies 4 48.64 Quite Low
Shock 1 47.28 Quite Low
Pruritus 24 32.64 Quite Low
INFLAMMATION 5 18.20 Low Low
Disease 4 5.00 Very Low Very Low Very Low
Hypersensitivity 4 5.00 Very Low Very Low Very Low
Erythema 3 5.00 Very Low Very Low Very Low
Skin Diseases 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Also Sema3A and NRP-1 of its receptors expressed in dendritic cells and T cells53,54 may be relevant to the immunological effect of Sema3A such as suppression of CD4+ T cells infiltration and IL-4 production observed in the AD-like lesions in NC/Nga mice treated with Sema3A, as above-mentioned.
Sema3A Negative_regulation (effect) of in T cells Gene_expression (production) of IL-4 in dendritic cells associated with eczema
1) Confidence 0.15 Published 2010 Journal Allergy, Asthma & Immunology Research Section Body Doc Link PMC2946701 Disease Relevance 0.48 Pain Relevance 0.14

General Comments

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