INT334537

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Context Info
Confidence 0.08
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 3.76
Pain Relevance 1.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Sema3a) signal transduction (Plxna1) extracellular region (Sema3a)
intracellular (Plxna1)
Anatomy Link Frequency
sensory neurons 4
Sema3a (Mus musculus)
Plxna1 (Mus musculus)
Pain Link Frequency Relevance Heat
Nerve growth factor 98 95.48 Very High Very High Very High
c fibre 6 92.72 High High
Antihistamine 4 84.24 Quite High
substance P 16 62.60 Quite High
antagonist 2 56.04 Quite High
cytokine 4 51.52 Quite High
Peripheral nervous system 2 38.24 Quite Low
Inflammation 14 18.80 Low Low
qutenza 6 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 8 99.12 Very High Very High Very High
Pruritus 48 97.28 Very High Very High Very High
Hypersensitivity 8 96.84 Very High Very High Very High
Eczema 216 91.84 High High
Skin Diseases 6 87.20 High High
Contact Dermatitis 2 46.32 Quite Low
Acanthosis 4 26.64 Quite Low
INFLAMMATION 10 18.80 Low Low
Congenital Anomalies 8 5.00 Very Low Very Low Very Low
Erythema 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Semaphorin 3A (Sema3A), an axon guidance molecule, is a potent inhibitor of neurite outgrowth of sensory neurons by exerting the plexin-A1-4 and neuropilin-1 (NRP-1) of its receptors.32,33 Fig. 10 shows semaphorin family and its receptors.
Sema3A Negative_regulation (inhibitor) of Gene_expression (exerting) of plexin-A1-4 in sensory neurons
1) Confidence 0.08 Published 2010 Journal Allergy, Asthma & Immunology Research Section Body Doc Link PMC2946701 Disease Relevance 1.87 Pain Relevance 0.50
Semaphorin 3A (Sema3A), an axon guidance molecule, is a potent inhibitor of neurite outgrowth of sensory neurons by exerting the plexin-A1-4 and neuropilin-1 (NRP-1) of its receptors.32,33 Fig. 10 shows semaphorin family and its receptors.
Semaphorin 3A Negative_regulation (inhibitor) of Gene_expression (exerting) of plexin-A1-4 in sensory neurons
2) Confidence 0.08 Published 2010 Journal Allergy, Asthma & Immunology Research Section Body Doc Link PMC2946701 Disease Relevance 1.88 Pain Relevance 0.50

General Comments

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