INT334664

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Context Info
Confidence 0.19
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.17
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

enzyme regulator activity (Psmd1) transport (Gria2) endoplasmic reticulum (Gria2)
plasma membrane (Gria2) cellular_component (Psmd1) protein complex (Gria2)
Gria2 (Mus musculus)
Psmd1 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 3 89.92 High High
amygdala 2 59.44 Quite High
Hippocampus 48 54.36 Quite High
long-term potentiation 45 5.00 Very Low Very Low Very Low
Pyramidal cell 12 5.00 Very Low Very Low Very Low
antagonist 5 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
nMDA receptor antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 28 100.00 Very High Very High Very High
Targeted Disruption 9 91.36 High High
Pain 3 89.92 High High
Shock 27 87.60 High High
Attention Deficit Hyperactivity Disorder 1 73.84 Quite High
Convulsion 7 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Aids-related Complex 2 5.00 Very Low Very Low Very Low
Body Weight 1 5.00 Very Low Very Low Very Low
Amnesia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results demonstrate that the loss of GluR2 in CA1 selectively impairs context fear (see Text S1 for a more detailed discussion).
Negative_regulation (loss) of GluR2 Negative_regulation (impairs) of Positive_regulation (see) of Text S1 associated with anxiety disorder
1) Confidence 0.19 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2947514 Disease Relevance 1.17 Pain Relevance 0.27

General Comments

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