INT334692

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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.89
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Igf1r) kinase activity (Igf1r)
Igf1r (Mus musculus)
Pain Link Frequency Relevance Heat
vincristine 7 60.08 Quite High
palliative 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sarcoma 52 99.52 Very High Very High Very High
Malignant Neoplastic Disease 2 87.28 High High
Disease 26 71.80 Quite High
Metastasis 35 70.96 Quite High
Apoptosis 2 57.20 Quite High
Male Infertility 1 51.92 Quite High
Reprotox - General 3 1 50.76 Quite High
Congenital Anomalies 1 34.92 Quite Low
Coronary Heart Disease 1 30.68 Quite Low
Cancer 45 25.36 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The role of insulin like growth factor-1 (IGF-1) and its receptor IGF-1R in the pathogenesis of Ewing’s sarcoma is well established.57 IGF-1R is found on the surface of most Ewing’s sarcoma cells and is necessary for the transforming ability of EWS-FLI fusion proteins.57 Thus, targeted therapy against IGF-1/ IGF-1R may be a very effective strategy in future.
Localization (found) of IGF-1R associated with sarcoma
1) Confidence 0.09 Published 2010 Journal Indian Journal of Orthopaedics Section Body Doc Link PMC2947722 Disease Relevance 0.89 Pain Relevance 0.03

General Comments

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