INT334780

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Context Info
Confidence 0.61
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 0.30
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Angptl4) extracellular space (Angptl4) extracellular region (Angptl4)
proteinaceous extracellular matrix (Angptl4)
Anatomy Link Frequency
F19 2
gut 2
Angptl4 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 40 91.52 High High
agonist 4 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
isoflurane 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colon Cancer 4 99.20 Very High Very High Very High
Weight Gain 12 69.72 Quite High
Obesity 48 67.84 Quite High
Sprains And Strains 12 44.28 Quite Low
Overweight 12 42.08 Quite Low
Body Weight 4 19.44 Low Low
Metabolic Syndrome 4 8.32 Low Low
Weight Loss 8 5.00 Very Low Very Low Very Low
Diabetes Mellitus 4 5.00 Very Low Very Low Very Low
Adenocarcinoma 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Combinatorial transfection of the different siRNAs did not result in cooperative effects on ANGPTL4 expression (data not shown).


Regulation (effects) of Gene_expression (expression) of ANGPTL4
1) Confidence 0.61 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2948012 Disease Relevance 0 Pain Relevance 0
The colon carcinoma cell line HCT116 was used to determine effects of selected gut microbiota on ANGPTL4 expression in colonocytes.
Spec (determine) Regulation (effects) of Gene_expression (expression) of ANGPTL4 in gut associated with colon cancer
2) Confidence 0.61 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2948012 Disease Relevance 0.24 Pain Relevance 0.09
, we still observed ANGPTL4 expression indicating that additional players are also regulating ANGPTL4 expression.
Regulation (regulating) of Gene_expression (expression) of ANGPTL4
3) Confidence 0.61 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2948012 Disease Relevance 0 Pain Relevance 0
Co-culture experiments of colonic cell lines and F19 were set up in order to monitor any ensuing alterations in ANGPTL4 expression by qPCR.
Regulation (alterations) of Gene_expression (expression) of ANGPTL4 in F19
4) Confidence 0.27 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2948012 Disease Relevance 0.07 Pain Relevance 0.04

General Comments

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