INT33479

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Context Info
Confidence 0.17
First Reported 1986
Last Reported 1986
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.15
Pain Relevance 0.73

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Oprl1) plasma membrane (Oprl1) kinase activity (Insrr)
signal transducer activity (Oprl1)
Oprl1 (Mus musculus)
Insrr (Mus musculus)
Pain Link Frequency Relevance Heat
opiate 2 100.00 Very High Very High Very High
antagonist 4 99.82 Very High Very High Very High
narcan 6 97.84 Very High Very High Very High
mu opioid receptor 1 76.20 Quite High
Spinal cord 2 75.00 Quite High
Opioid 1 72.28 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This finding suggests that antagonist-induced opiate receptor upregulation does not require the synthesis of new receptor molecules.
Positive_regulation (upregulation) of opiate receptor Neg (not) Positive_regulation (require) of Gene_expression (synthesis) of receptor associated with antagonist and opiate
1) Confidence 0.17 Published 1986 Journal Brain Res. Section Abstract Doc Link 3006869 Disease Relevance 0.15 Pain Relevance 0.73

General Comments

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