INT33490

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Context Info
Confidence 0.02
First Reported 1986
Last Reported 1986
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.62
Pain Relevance 0.84

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Krt2) structural molecule activity (Krt2) molecular_function (Krt2)
cellular_component (Krt2) biological_process (Krt2) cytoplasm (Krt2)
Anatomy Link Frequency
stem 1
Krt2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Clonidine 12 100.00 Very High Very High Very High
noradrenaline 2 85.12 High High
Disease Link Frequency Relevance Heat
Hypertension 10 98.62 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In vasopressin-hypertensive rats neither small nor large doses of clonidine were able to induce changes in type II inhibitor activity suggesting subsensitivity of pre- and postsynaptic alpha 2-adrenoceptors.
Regulation (changes) of type II associated with hypertension and clonidine
1) Confidence 0.02 Published 1986 Journal Eur. J. Pharmacol. Section Abstract Doc Link 3007171 Disease Relevance 0.41 Pain Relevance 0.53
When administered to rats, the effect of clonidine on type II inhibitor activity in the hypothalamus and brain-stem depended on the dose.
Regulation (effect) of type II in stem associated with clonidine
2) Confidence 0.02 Published 1986 Journal Eur. J. Pharmacol. Section Abstract Doc Link 3007171 Disease Relevance 0.20 Pain Relevance 0.31

General Comments

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