INT334901

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.48
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Crp) transport (LDLR) small molecule metabolic process (LDLR)
plasma membrane (LDLR) lipid metabolic process (LDLR) lysosome (LDLR)
LDLR (Homo sapiens)
Crp (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 25 96.30 Very High Very High Very High
Inflammatory marker 3 95.70 Very High Very High Very High
Arthritis 13 93.56 High High
Inflammation 25 88.88 High High
cytokine 1 45.88 Quite Low
cINOD 6 5.00 Very Low Very Low Very Low
corticosteroid 5 5.00 Very Low Very Low Very Low
spinal inflammation 5 5.00 Very Low Very Low Very Low
methotrexate 4 5.00 Very Low Very Low Very Low
COX-2 inhibitor 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 26 96.30 Very High Very High Very High
INFLAMMATION 29 95.54 Very High Very High Very High
Autoimmune Disease 1 87.84 High High
Nicotine Addiction 3 73.40 Quite High
Metabolic Disorder 1 66.36 Quite High
Disease 19 62.80 Quite High
Arthritis 17 56.64 Quite High
Atherosclerosis 8 52.64 Quite High
Arthropathy 1 36.32 Quite Low
Diabetes Mellitus 1 25.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The TARA (Trial of Atorvastatin in Rheumatoid Arthritis) study [8] showed that atorvastatin for 6 months had a significant effect on lowering inflammatory markers, and subsequently in a non-RA study, the Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) trial, rosuvastatin treatment in healthy individuals with normal low-density lipoprotein (LDL) cholesterol but elevated C-reactive protein (CRP) (>2 mg/L) was found to reduce cardiac events by nearly half.
low-density lipoprotein Positive_regulation (elevated) of CRP associated with inflammatory marker, rheumatoid arthritis and arthritis
1) Confidence 0.00 Published 2010 Journal F1000 Med Rep Section Body Doc Link PMC2948399 Disease Relevance 1.48 Pain Relevance 0.51

General Comments

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