INT334903

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.83
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Chrna7) plasma membrane (Chrna7) cytoplasm (Chrna7)
Chrna7 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
long-term potentiation 39 79.72 Quite High
Botox 1 79.52 Quite High
depression 36 79.08 Quite High
agonist 5 5.00 Very Low Very Low Very Low
Transcranial magnetic stimulation 4 5.00 Very Low Very Low Very Low
Spinal cord 3 5.00 Very Low Very Low Very Low
Eae 3 5.00 Very Low Very Low Very Low
transdermal 3 5.00 Very Low Very Low Very Low
medulla 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Overactive Bladder 71 100.00 Very High Very High Very High
Clostridium Infection 1 82.92 Quite High
Depression 36 79.08 Quite High
Bladder Disease 2 74.56 Quite High
Pollakiuria 4 59.32 Quite High
Urge Incontinence 12 49.80 Quite Low
Reprotox - General 2 5 42.12 Quite Low
Dystonia 28 19.12 Low Low
Xerostomia 6 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
BTX is not approved for the treatment of OAB but is now widely used in patients who are refractory to conventional antimuscarinic therapy or who do not tolerate it due to systemic side effects.
Neg (not) Positive_regulation (approved) of Localization (used) of BTX associated with overactive bladder
1) Confidence 0.04 Published 2010 Journal F1000 Med Rep Section Body Doc Link PMC2948402 Disease Relevance 0.68 Pain Relevance 0.04
Clinical results in patients before and after BTX treatment
Positive_regulation (after) of Localization (treatment) of BTX
2) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2964285 Disease Relevance 0.15 Pain Relevance 0.19

General Comments

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