INT334907

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Context Info
Confidence 0.56
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 5
Disease Relevance 8.28
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Nppb) extracellular region (Nppb) nucleus (Nppb)
cytoplasm (Nppb)
Nppb (Mus musculus)
Pain Link Frequency Relevance Heat
Angina 28 99.20 Very High Very High Very High
Pain 3 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Mitral Valve Insufficiency 312 99.98 Very High Very High Very High
Acute Coronary Syndrome 104 99.84 Very High Very High Very High
Cv General 3 Under Development 28 99.20 Very High Very High Very High
Hypertension 70 98.80 Very High Very High Very High
Heart Rate Under Development 52 97.04 Very High Very High Very High
Myocardial Infarction 80 96.72 Very High Very High Very High
Natriuresis 22 94.64 High High
Death 27 91.16 High High
Thalassemia 25 91.08 High High
Diabetes Mellitus 8 84.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although we cannot exclude some degradation of BNP over time, only a very weak relation to days of storage was noted.
Protein_catabolism (degradation) of BNP
1) Confidence 0.56 Published 2010 Journal Heart Section Body Doc Link PMC2976074 Disease Relevance 1.05 Pain Relevance 0
The proBNP hormone is cleaved into the biologically active BNP and an easily measurable inactive amino-terminal proBNP.
Neg (inactive) Protein_catabolism (cleaved) of proBNP
2) Confidence 0.51 Published 2010 Journal F1000 Med Rep Section Body Doc Link PMC2948405 Disease Relevance 2.48 Pain Relevance 0
In a multivariate model including MR grade >1, LVEF <0.40 and BNP >373?
Protein_catabolism (grade) of BNP associated with mitral valve insufficiency
3) Confidence 0.32 Published 2010 Journal Heart Section Abstract Doc Link PMC2976074 Disease Relevance 1.57 Pain Relevance 0
Indeed, in the current study we show for the first time that the prognostic information obtained from MR grade and BNP in ACS is complementary and significant when LVEF is also considered.
Protein_catabolism (grade) of BNP associated with acute coronary syndrome and mitral valve insufficiency
4) Confidence 0.32 Published 2010 Journal Heart Section Body Doc Link PMC2976074 Disease Relevance 1.74 Pain Relevance 0
Hypertension and previous angina were more common in the groups with MR grade >1 and higher BNP, while there was no difference between the LVEF subgroups.
Protein_catabolism (grade) of BNP associated with angina, mitral valve insufficiency and hypertension
5) Confidence 0.32 Published 2010 Journal Heart Section Body Doc Link PMC2976074 Disease Relevance 1.45 Pain Relevance 0.22

General Comments

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