INT334918

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Context Info
Confidence 0.11
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.27
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (FSHR) signal transduction (GNRH1) extracellular space (GNRH1)
extracellular region (GNRH1) plasma membrane (FSHR) signal transducer activity (FSHR)
Anatomy Link Frequency
follicle 2
GNRH1 (Homo sapiens)
FSHR (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 1 56.56 Quite High
Dismenorea 1 23.92 Low Low
corticosteroid 7 5.00 Very Low Very Low Very Low
transdermal 6 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Opioid 3 5.00 Very Low Very Low Very Low
Lasting pain 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Polycystic Ovary Syndrome 52 99.60 Very High Very High Very High
Hypogonadotropic Hypogonadism 73 84.24 Quite High
Injury 3 83.04 Quite High
Aging 5 80.48 Quite High
Syndrome 8 62.20 Quite High
Obesity 29 55.48 Quite High
Hyperinsulinism 4 53.44 Quite High
Acanthosis 1 52.08 Quite High
Alopecia 7 50.84 Quite High
Acne 1 49.76 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The hypothalamus secretes gonadotropin-releasing hormone (GnRH) that acts on the anterior pituitary to produce follicle-stimulating hormone (FSH) and luteinizing hormone (LH).
GnRH Positive_regulation (acts) of Gene_expression (produce) of FSH in follicle
1) Confidence 0.11 Published 2010 Journal International Journal of Clinical Practice Section Body Doc Link PMC2948422 Disease Relevance 0.52 Pain Relevance 0
High GnRH expression increases LH and low GnRH increases FSH synthesis.
GnRH Positive_regulation (increases) of Gene_expression (synthesis) of FSH
2) Confidence 0.07 Published 2010 Journal International Journal of Trichology Section Body Doc Link PMC3002408 Disease Relevance 0.75 Pain Relevance 0.03

General Comments

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