INT33497

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Context Info
Confidence 0.27
First Reported 1986
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.10
Pain Relevance 0.79

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

carbohydrate metabolic process (Man2a2)
Anatomy Link Frequency
jaw 2
Man2a2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
opiate 6 100.00 Very High Very High Very High
Clonidine 4 100.00 Very High Very High Very High
methadone 4 76.48 Quite High
agonist 3 73.52 Quite High
antagonist 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Stress 3 98.84 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We assessed in the rat the effects of either single or repeated tail pinch on clonidine-induced inhibition of the jaw-opening reflex (JOR) via activation of postsynaptic central alpha2-adrenoceptors.
Regulation (effects) of Positive_regulation (activation) of alpha2-adrenoceptors in jaw associated with clonidine
1) Confidence 0.27 Published 1998 Journal Psychopharmacology (Berl.) Section Abstract Doc Link 9694532 Disease Relevance 0.10 Pain Relevance 0.28
In adult rats, the noradrenergic system plays a role in pulsatile and opiate-stimulated growth hormone (GH) secretion through stimulation of alpha-2 adrenergic receptors.
Regulation (plays) of Positive_regulation (stimulation) of alpha-2 associated with opiate
2) Confidence 0.04 Published 1986 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 3007734 Disease Relevance 0 Pain Relevance 0.52

General Comments

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