INT334993

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Context Info
Confidence 0.38
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 4.10
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Fgf23) extracellular space (Fgf23) extracellular region (Fgf23)
Fgf23 (Mus musculus)
Pain Link Frequency Relevance Heat
Bile 48 49.96 Quite Low
cytokine 3 5.00 Very Low Very Low Very Low
Spinal cord 3 5.00 Very Low Very Low Very Low
agonist 3 5.00 Very Low Very Low Very Low
sodium channel 3 5.00 Very Low Very Low Very Low
Eae 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rickets 54 99.78 Very High Very High Very High
Calcification 18 96.48 Very High Very High Very High
Targeted Disruption 111 94.00 High High
Hypophosphatemia 12 93.20 High High
Metabolic Disorder 24 89.28 High High
Eating Disorder 3 84.92 Quite High
Cancer 15 83.28 Quite High
Syndrome 3 80.32 Quite High
Disease 18 76.32 Quite High
Obesity 51 75.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Fgf23 mutations in ADHR result in impaired proteolytic processing of Fgf23 and increased active Fgf23 levels in serum (TableĀ 2) (White et al. 2001).
Negative_regulation (impaired) of Gene_expression (processing) of Fgf23 associated with rickets
1) Confidence 0.38 Published 2010 Journal Cell Tissue Res Section Body Doc Link PMC2948652 Disease Relevance 1.44 Pain Relevance 0
Fgf23 mutations in ADHR result in impaired proteolytic processing of Fgf23 and increased active Fgf23 levels in serum (TableĀ 2) (White et al. 2001).
Negative_regulation (impaired) of Gene_expression (processing) of Fgf23 associated with rickets
2) Confidence 0.33 Published 2010 Journal Cell Tissue Res Section Body Doc Link PMC2948652 Disease Relevance 1.51 Pain Relevance 0
The loss-of-function mutation of Galnt3 impairs secretion of intact Fgf23, leading to decreased serum Fgf23 levels and hyperphosphatemia (Ichikawa et al. 2009).
Negative_regulation (decreased) of Gene_expression (levels) of Fgf23
3) Confidence 0.33 Published 2010 Journal Cell Tissue Res Section Body Doc Link PMC2948652 Disease Relevance 1.15 Pain Relevance 0

General Comments

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