INT334999

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Context Info
Confidence 0.43
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 2.33
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Fgf21)
Anatomy Link Frequency
liver 1
adipose tissue 1
Fgf21 (Mus musculus)
Pain Link Frequency Relevance Heat
Bile 48 73.44 Quite High
cytokine 3 5.00 Very Low Very Low Very Low
Spinal cord 3 5.00 Very Low Very Low Very Low
agonist 3 5.00 Very Low Very Low Very Low
sodium channel 3 5.00 Very Low Very Low Very Low
Eae 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 51 99.44 Very High Very High Very High
Targeted Disruption 111 97.76 Very High Very High Very High
Fatty Liver 15 93.08 High High
Hypertrophy 3 78.96 Quite High
Rickets 54 5.00 Very Low Very Low Very Low
Metabolic Disorder 24 5.00 Very Low Very Low Very Low
Calcification 18 5.00 Very Low Very Low Very Low
Disease 18 5.00 Very Low Very Low Very Low
Cancer 15 5.00 Very Low Very Low Very Low
Hypophosphatemia 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results indicate that Fgf21 regulates lipolysis in adipocytes in response to the metabolic state but is not required for ketogenesis or triglyceride clearance in the liver (TableĀ 1).
Regulation (regulates) of Fgf21 in liver associated with obesity
1) Confidence 0.43 Published 2010 Journal Cell Tissue Res Section Body Doc Link PMC2948652 Disease Relevance 1.08 Pain Relevance 0
These results suggest that Fgf21 acts as a metabolic regulator of lipolysis in the white adipose tissue and is required for ketogenesis and triglyceride clearance in the liver.
Regulation (regulator) of Fgf21 in adipose tissue associated with obesity
2) Confidence 0.43 Published 2010 Journal Cell Tissue Res Section Body Doc Link PMC2948652 Disease Relevance 1.02 Pain Relevance 0
The regulatory process forms a negative feedback loop in the regulation of vitamin D homeostasis

Fgf21

Regulation (regulation) of Fgf21
3) Confidence 0.37 Published 2010 Journal Cell Tissue Res Section Body Doc Link PMC2948652 Disease Relevance 0.23 Pain Relevance 0.09

General Comments

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