INT335018

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Context Info
Confidence 0.44
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.36
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Fgf23) cytosol (Vdr) extracellular space (Fgf23)
extracellular region (Fgf23) cell morphogenesis (Vdr) nucleus (Vdr)
Vdr (Mus musculus)
Fgf23 (Mus musculus)
Pain Link Frequency Relevance Heat
Bile 32 85.04 High High
agonist 2 61.04 Quite High
cytokine 2 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
sodium channel 2 5.00 Very Low Very Low Very Low
Eae 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 34 73.36 Quite High
Targeted Disruption 74 56.04 Quite High
Disease 12 52.64 Quite High
Extrahepatic Cholestasis 2 46.88 Quite Low
Pancreatic Cancer 2 43.92 Quite Low
Toxicity 2 25.92 Quite Low
Weight Gain 2 12.64 Low Low
Heart Defects 2 10.64 Low Low
Rickets 36 5.00 Very Low Very Low Very Low
Metabolic Disorder 16 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The ligand-bound VDR forms a heterodimer with retinoid X receptors (RXRs) and induces the expression of Fgf23.
VDR Positive_regulation (induces) of Gene_expression (expression) of Fgf23
1) Confidence 0.44 Published 2010 Journal Cell Tissue Res Section Body Doc Link PMC2948652 Disease Relevance 0.18 Pain Relevance 0.14
The ligand-bound VDR forms a heterodimer with retinoid X receptors (RXRs) and induces the expression of Fgf23 in the bone.
VDR Positive_regulation (induces) of Gene_expression (expression) of Fgf23
2) Confidence 0.29 Published 2010 Journal Cell Tissue Res Section Body Doc Link PMC2948652 Disease Relevance 0.18 Pain Relevance 0.03

General Comments

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