INT335020

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.62
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.82
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Fgf23) mitochondrion (Cyp24a1) extracellular space (Fgf23)
oxidoreductase activity (Cyp24a1) extracellular region (Fgf23)
Anatomy Link Frequency
kidney 2
Fgf23 (Mus musculus)
Cyp24a1 (Mus musculus)
Pain Link Frequency Relevance Heat
Bile 48 80.72 Quite High
agonist 3 56.64 Quite High
cytokine 3 5.00 Very Low Very Low Very Low
Spinal cord 3 5.00 Very Low Very Low Very Low
sodium channel 3 5.00 Very Low Very Low Very Low
Eae 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 18 80.32 Quite High
Obesity 51 79.84 Quite High
Extrahepatic Cholestasis 3 74.56 Quite High
Pancreatic Cancer 3 71.60 Quite High
Targeted Disruption 111 56.08 Quite High
Toxicity 3 53.60 Quite High
Fatty Liver 15 31.36 Quite Low
Insulin Resistance 3 22.80 Low Low
Weight Gain 3 8.24 Low Low
Heart Defects 3 6.32 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The increased Fgf23 suppresses the expression of Cyp27b1 and induces the expression of Cyp24 by activating the ?
Fgf23 Positive_regulation (induces) of Gene_expression (expression) of Cyp24
1) Confidence 0.62 Published 2010 Journal Cell Tissue Res Section Body Doc Link PMC2948652 Disease Relevance 0.20 Pain Relevance 0.13
The Fgf23 suppresses the expression of Cyp27b1 and induces the expression of Cyp24 in the kidney (Shimada et al 2004).
Fgf23 Positive_regulation (induces) of Gene_expression (expression) of Cyp24 in kidney
2) Confidence 0.41 Published 2010 Journal Cell Tissue Res Section Body Doc Link PMC2948652 Disease Relevance 0.29 Pain Relevance 0.03
The suppression of Cyp27b1 expression and induction of Cyp24 expression by Fgf23 result in decreased levels of active vitamin D in serum.
Fgf23 Positive_regulation (induction) of Gene_expression (expression) of Cyp24
3) Confidence 0.41 Published 2010 Journal Cell Tissue Res Section Body Doc Link PMC2948652 Disease Relevance 0.34 Pain Relevance 0.03

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox