INT335105

Context Info Confidence 0.21 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0.71 Pain Relevance 0.33

signal transduction (VLDLR) transport (VLDLR) extracellular space (VLDLR) plasma membrane (VLDLR) nucleus (VLDLR)

Anatomy Link Frequency muscle 1 adipose tissue 1 VLDLR (Homo sapiens)

Pain Link Frequency Relevance Heat agonist 60 97.40 Inflammation 28 5.00 Bile 18 5.00 Inflammatory response 4 5.00 Endocannabinoid 4 5.00 COX2 2 5.00 cINOD 2 5.00 Inflammatory mediators 2 5.00 antagonist 2 5.00

Disease Link Frequency Relevance Heat Disorder Of Lipid Metabolism 28 99.80 Obesity 28 94.76 INFLAMMATION 32 5.00 Nash(non-alcoholic Steatohepatitis) 6 5.00 Fatty Liver 4 5.00 Hepatocellular Cancer 4 5.00 Alzheimer's Dementia 4 5.00 Dyslipidemia / Combined Dyslipidemia 4 5.00 Hypoglycemia 4 5.00 Liver Disease 2 5.00

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Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Clearance of TG-rich lipoproteins VLDL and chylomicrons is mediated by the enzyme lipoprotein lipase (LPL), which is attached to the capillary endothelium of muscle and adipose tissue.

Localization (Clearance) of TG-rich lipoproteins VLDL in adipose tissue associated with obesity and disorder of lipid metabolism

1) Confidence 0.21 Published 2010 Journal PPAR Research Section Body Doc Link PMC2948931 Disease Relevance 0.36 Pain Relevance 0.17

Clearance of TG-rich lipoproteins VLDL and chylomicrons is mediated by the enzyme lipoprotein lipase (LPL), which is attached to the capillary endothelium of muscle and adipose tissue.

Localization (Clearance) of TG-rich lipoproteins VLDL in muscle associated with obesity and disorder of lipid metabolism

2) Confidence 0.07 Published 2010 Journal PPAR Research Section Body Doc Link PMC2948931 Disease Relevance 0.36 Pain Relevance 0.17

General Comments

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