INT335109

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Context Info
Confidence 0.68
First Reported 2010
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.53
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (ANGPTL4) signal transduction (ANGPTL4) extracellular space (ANGPTL4)
small molecule metabolic process (ANGPTL4) extracellular region (ANGPTL4) proteinaceous extracellular matrix (ANGPTL4)
Anatomy Link Frequency
plasma 1
ANGPTL4 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 76 88.12 High High
Inflammation 38 5.00 Very Low Very Low Very Low
fibrosis 10 5.00 Very Low Very Low Very Low
Bile 9 5.00 Very Low Very Low Very Low
cytokine 8 5.00 Very Low Very Low Very Low
cINOD 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Endocannabinoid 2 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 34 83.28 Quite High
Disorder Of Lipid Metabolism 14 75.96 Quite High
Obesity 14 67.92 Quite High
INFLAMMATION 42 5.00 Very Low Very Low Very Low
Cancer 23 5.00 Very Low Very Low Very Low
Fibrosis 12 5.00 Very Low Very Low Very Low
Stress 10 5.00 Very Low Very Low Very Low
Diabetes Mellitus 3 5.00 Very Low Very Low Very Low
Nash(non-alcoholic Steatohepatitis) 3 5.00 Very Low Very Low Very Low
Metastasis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This correlates well with the observed changes in ANGPTL4 expression, pointing to a causal relationship between the regulation of class A genes and the recruitment of SMRT in response to TGF?
Gene_expression (expression) of ANGPTL4
1) Confidence 0.68 Published 2011 Journal Nucleic Acids Research Section Body Doc Link PMC3017614 Disease Relevance 0.06 Pain Relevance 0
and GW501516-regulated ANGPTL4 and PDK4 gene expression.
Gene_expression (expression) of ANGPTL4
2) Confidence 0.68 Published 2011 Journal Nucleic Acids Research Section Body Doc Link PMC3017614 Disease Relevance 0.08 Pain Relevance 0
upregulates hepatic expression and plasma levels of Angptl4, which acts as inhibitor of LPL activity by converting active LPL dimers to inactive monomers [126].
Gene_expression (expression) of Angptl4 in plasma
3) Confidence 0.46 Published 2010 Journal PPAR Research Section Body Doc Link PMC2948931 Disease Relevance 0.38 Pain Relevance 0.11

General Comments

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