INT335126

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Context Info
Confidence 0.24
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.72
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Ptgs2, PPARA) nucleus (Ptgs2, PPARA) nucleoplasm (PPARA)
small molecule metabolic process (PPARA) endoplasmic reticulum (Ptgs2) DNA binding (PPARA)
Ptgs2 (Mus musculus)
PPARA (Homo sapiens)
Pain Link Frequency Relevance Heat
COX2 1 100.00 Very High Very High Very High
Inflammation 14 95.36 Very High Very High Very High
agonist 30 86.52 High High
Inflammatory mediators 1 24.76 Low Low
cINOD 1 16.88 Low Low
Bile 9 13.76 Low Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Endocannabinoid 2 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fatty Liver 2 96.96 Very High Very High Very High
INFLAMMATION 16 95.36 Very High Very High Very High
Nash(non-alcoholic Steatohepatitis) 3 90.96 High High
Liver Disease 1 88.88 High High
Cirrhosis 1 84.72 Quite High
Colon Cancer 1 34.84 Quite Low
Colitis 1 33.88 Quite Low
Cancer 1 32.88 Quite Low
Obesity 14 5.00 Very Low Very Low Very Low
Disorder Of Lipid Metabolism 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
on progression of steatosis to steatohepatitis may be mediated in part by COX2 (Ptgs2), a candidate gene involved in steatohepatitis development that is suppressed by PPAR?
Ptgs2 Positive_regulation (mediated) of Gene_expression (suppressed) of PPAR associated with cox2
1) Confidence 0.24 Published 2010 Journal PPAR Research Section Body Doc Link PMC2948931 Disease Relevance 0.72 Pain Relevance 0.25

General Comments

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