INT335291

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.45
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (NFATC1) DNA binding (NFATC1) cytoplasm (NFATC1)
transmembrane transport (SLC15A4)
SLC15A4 (Homo sapiens)
NFATC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Calcium channel 2 94.00 High High
Inflammation 14 91.68 High High
cytokine 36 90.64 High High
Inflammatory response 2 75.20 Quite High
sodium channel 10 70.16 Quite High
metalloproteinase 6 50.00 Quite Low
anticonvulsant 4 5.00 Very Low Very Low Very Low
tetrodotoxin 2 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Antiepileptic agent 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 16 91.68 High High
Multiple Sclerosis 2 77.52 Quite High
Gingival Overgrowth 20 10.24 Low Low
Pathologic Processes 4 5.00 Very Low Very Low Very Low
Wound Healing 4 5.00 Very Low Very Low Very Low
Convulsion 4 5.00 Very Low Very Low Very Low
Fibrosis 2 5.00 Very Low Very Low Very Low
Periodontal Disease 2 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Hyperplasia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Kiode et al [57] suggested that PHT may inhibit NFATc1 signals through suppression of c-fos expression.
PHT Spec (may) Negative_regulation (inhibit) of NFATc1
1) Confidence 0.01 Published 2010 Journal J Inflamm (Lond) Section Body Doc Link PMC2949711 Disease Relevance 0.22 Pain Relevance 0.26
PHT was also shown to inhibit NFATc1 signaling in these cells.
PHT Negative_regulation (inhibit) of NFATc1
2) Confidence 0.01 Published 2010 Journal J Inflamm (Lond) Section Body Doc Link PMC2949711 Disease Relevance 0.22 Pain Relevance 0.25

General Comments

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