INT335433

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Context Info
Confidence 0.28
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.45
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Cysltr2, Trpv1) cytosol (Trpv1) molecular_function (Cysltr2)
cellular_component (Cysltr2) lipid metabolic process (Trpv1) signal transducer activity (Cysltr2)
Anatomy Link Frequency
primary sensory neurons 1
Cysltr2 (Rattus norvegicus)
Trpv1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Kinase C 3 97.64 Very High Very High Very High
Thermal hyperalgesia 10 96.44 Very High Very High Very High
unmyelinated 4 70.12 Quite High
Calcitonin gene-related peptide 9 65.64 Quite High
Inflammation 9 64.96 Quite High
dorsal root ganglion 30 55.40 Quite High
Pain 8 54.24 Quite High
nociceptor 3 48.72 Quite Low
Spinal cord 4 31.76 Quite Low
Hyperalgesia 2 13.00 Low Low
Disease Link Frequency Relevance Heat
Hyperalgesia 12 96.44 Very High Very High Very High
INFLAMMATION 9 64.96 Quite High
Ganglion Cysts 31 55.40 Quite High
Pain 8 54.24 Quite High
Apoptosis 1 45.40 Quite Low
Hypersensitivity 1 21.76 Low Low
Nociception 6 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 4 5.00 Very Low Very Low Very Low
Inflammatory Pain 3 5.00 Very Low Very Low Very Low
Decapitation 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because it is possible that CysLT2 can sensitize TRPV1 in primary sensory neurons, we examined whether intraplantar injection of LTC4 leads to thermal hyperalgesia.
CysLT2 Regulation (sensitize) of TRPV1 in primary sensory neurons associated with thermal hyperalgesia
1) Confidence 0.28 Published 2010 Journal Mol Pain Section Body Doc Link PMC2949724 Disease Relevance 0.45 Pain Relevance 0.55

General Comments

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