INT335441

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Context Info
Confidence 0.20
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.91
Pain Relevance 0.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Cpm) plasma membrane (Cpm) nucleus (Cpm)
molecular_function (Cpm) biological_process (Cpm) cytoplasm (Cpm)
Cpm (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 75 99.98 Very High Very High Very High
Hyperalgesia 13 96.04 Very High Very High Very High
Lasting pain 1 83.68 Quite High
c fibre 33 77.20 Quite High
qutenza 3 76.52 Quite High
Inflammatory mediators 4 71.96 Quite High
Peripheral nerve injury 1 27.84 Quite Low
nociceptor 13 5.00 Very Low Very Low Very Low
Thermal hyperalgesia 5 5.00 Very Low Very Low Very Low
Spinal cord 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 80 99.98 Very High Very High Very High
Sprains And Strains 3 98.68 Very High Very High Very High
Hyperalgesia 18 96.04 Very High Very High Very High
Injury 5 92.16 High High
Pain 4 83.68 Quite High
Nervous System Injury 3 26.96 Quite Low
Pressure And Volume Under Development 6 5.00 Very Low Very Low Very Low
Neuropathic Pain 3 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Neurogenic Inflammation 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study we found that inflammation induced sensitization of TRPV1-negative CPM-fibers to heat in two different strains of wildtype mice and this change was correlated with heat hyperalgesia in the C57/Bl6 mice.
Positive_regulation (induced) of CPM associated with hyperalgesia, inflammation and sprains and strains
1) Confidence 0.20 Published 2010 Journal Mol Pain Section Body Doc Link PMC2949725 Disease Relevance 0.91 Pain Relevance 0.65

General Comments

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