INT335459

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (ABCA1, ITPR3) nucleoplasm (ITPR3) transport (ABCA1)
endoplasmic reticulum (ITPR3) Golgi apparatus (ABCA1) intracellular (ABCA1)
Anatomy Link Frequency
reticulum 1
ABCA1 (Homo sapiens)
ITPR3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Calcium channel 1 97.72 Very High Very High Very High
Kinase C 17 87.92 High High
agonist 7 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypersensitivity 14 5.00 Very Low Very Low Very Low
INFLAMMATION 6 5.00 Very Low Very Low Very Low
Hypertension 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Disease Susceptibility 1 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low
Anaphylaxis 1 5.00 Very Low Very Low Very Low
Chronic Disease 1 5.00 Very Low Very Low Very Low
Leukemia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
While DAG remains to the membrane, IP3 diffuses to the cytosol and binds to and activates the InsP3 receptor on the membrane of the endoplasmic reticulum, opening a calcium channel, resulting in the release of Ca2+ into the cytoplasm.
membrane Positive_regulation (activates) of InsP3 receptor in reticulum associated with calcium channel
1) Confidence 0.00 Published 2010 Journal Clin Mol Allergy Section Body Doc Link PMC2949734 Disease Relevance 0 Pain Relevance 0.15

General Comments

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