INT335486

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Context Info
Confidence 0.36
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (CD63) plasma membrane (CD63)
Anatomy Link Frequency
basophils 2
CD63 (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 17 97.58 Very High Very High Very High
agonist 7 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Calcium channel 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypersensitivity 14 5.00 Very Low Very Low Very Low
INFLAMMATION 6 5.00 Very Low Very Low Very Low
Hypertension 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Disease Susceptibility 1 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low
Anaphylaxis 1 5.00 Very Low Very Low Very Low
Chronic Disease 1 5.00 Very Low Very Low Very Low
Leukemia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In our assay system the flavonol proved insensitive to target protein kinase C (PKC), as resulted from the use of PMA as basophil stimulant, thus confirming previous reports [19]: quercetin was unable to inhibit CD63 and CD203c membrane up-regulation in basophils stimulated with phorbol esters and no dissociation between the two markers investigated was actually observed by using PMA [45].
Negative_regulation (inhibit) of Positive_regulation (up-regulation) of CD63 in basophils associated with kinase c
1) Confidence 0.36 Published 2010 Journal Clin Mol Allergy Section Body Doc Link PMC2949734 Disease Relevance 0 Pain Relevance 0.28

General Comments

This test has worked.

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