INT335653

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.24
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
thyroid gland 1
parenchyma 1
Tg(EGFR)4Jlj (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 2 43.84 Quite Low
depression 2 43.36 Quite Low
Disease Link Frequency Relevance Heat
Thyroiditis 2 88.48 High High
Thyroid Disease 10 82.56 Quite High
Pain 2 43.84 Quite Low
Depression 2 43.36 Quite Low
Anxiety Disorder 4 42.40 Quite Low
Fatigue 2 41.68 Quite Low
Body Weight 2 39.60 Quite Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low
Obesity 4 5.00 Very Low Very Low Very Low
Hypertension 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, for decades it has been known that T4 can be activated outside the thyroid gland to T3 via iodothyronine deiodinases D1 and D2.
Positive_regulation (activated) of T4 in thyroid gland
1) Confidence 0.07 Published 2010 Journal F1000 Med Rep Section Body Doc Link PMC2950057 Disease Relevance 0.06 Pain Relevance 0
This rationale stems from the existence of iodothyronine deiodinases, enzymes that activate thyroxine (T4) to T3 outside of the thyroid parenchyma and generate most of the circulating T3 [3].
Positive_regulation (activate) of T4 in parenchyma
2) Confidence 0.07 Published 2010 Journal F1000 Med Rep Section Body Doc Link PMC2950057 Disease Relevance 0.17 Pain Relevance 0

General Comments

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