INT335732

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Context Info
Confidence 0.57
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.87
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Vcp) cytosol (Vcp) transport (Vcp)
endoplasmic reticulum (Vcp) ATPase activity (Vcp) nucleus (Vcp)
Anatomy Link Frequency
muscle 2
Vcp (Mus musculus)
Vcp - R155H (1)
Pain Link Frequency Relevance Heat
Eae 5 5.00 Very Low Very Low Very Low
Hippocampus 4 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 95 99.88 Very High Very High Very High
Muscle Weakness 17 96.60 Very High Very High Very High
Frontotemporal Dementia 8 79.04 Quite High
Disease 27 67.32 Quite High
Muscle Disease 10 56.12 Quite High
Brain Disease 3 45.28 Quite Low
Apoptosis 24 26.04 Quite Low
Convulsion 13 5.00 Very Low Very Low Very Low
Bone Disease 12 5.00 Very Low Very Low Very Low
Cognitive Disorder 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Transgenic mice overexpressing R155H VCP under a muscle-specific promoter, reported by Weihl et al (2006) [31], demonstrated muscle weakness, and slit-like vacuoles.
Positive_regulation (overexpressing) of Gene_expression (overexpressing) of R155H VCP (R155H) in muscle associated with targeted disruption and muscle weakness
1) Confidence 0.57 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2950155 Disease Relevance 0.87 Pain Relevance 0

General Comments

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