INT335735

Context Info Confidence 0.03 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 1.17 Pain Relevance 0.24

ATPase activity (Atp13a3) molecular_function (Atp13a3) cellular_component (Atp13a3)

Anatomy Link Frequency interneurons 1 Atp13a3 (Mus musculus)

Pain Link Frequency Relevance Heat ketamine 75 98.40 Pain 1 52.44 Pyramidal cell 59 28.52 Hippocampus 17 5.00 anesthesia 12 5.00 Eae 5 5.00 interneuron 4 5.00 Limbic system 4 5.00 imagery 3 5.00 nMDA receptor 2 5.00

Disease Link Frequency Relevance Heat Disease 27 96.44 Respiratory Failure 1 89.04 Muscle Weakness 17 87.08 Agraphia 1 84.36 Dyslexia 1 83.80 Apoptosis 24 75.68 Anomia 1 75.68 Frontotemporal Dementia 8 71.16 Unconsciousness 14 69.36 Dementia 3 69.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

VCP belongs to the family of type II ATPase associated with variety of cellular activities (AAA) having two ATPase domains [15]–[19].

type II ATPase Binding (associated) of

1) Confidence 0.03 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2950155 Disease Relevance 1.10 Pain Relevance 0.05

But both type-5 and type-6 interneurons responded with rhythmic dynamics after ketamine injection.

type-5 Binding (interneurons) of in interneurons associated with ketamine

2) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2999569 Disease Relevance 0.07 Pain Relevance 0.19

General Comments

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