INT335736

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Context Info
Confidence 0.19
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.36
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (Map1lc3a, Map1lc3b) cytoplasm (Map1lc3a, Map1lc3b) cytosol (Map1lc3a)
intracellular (Map1lc3b)
Anatomy Link Frequency
cleavage 1
Map1lc3a (Mus musculus)
Map1lc3b (Mus musculus)
Pain Link Frequency Relevance Heat
Eae 5 5.00 Very Low Very Low Very Low
Hippocampus 4 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 95 85.92 High High
Apoptosis 24 85.04 High High
Disease 27 50.00 Quite Low
Muscle Disease 10 50.00 Quite Low
Pressure And Volume Under Development 2 42.68 Quite Low
Death 1 9.84 Low Low
Muscle Weakness 17 5.00 Very Low Very Low Very Low
Convulsion 13 5.00 Very Low Very Low Very Low
Bone Disease 12 5.00 Very Low Very Low Very Low
Frontotemporal Dementia 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Upon activation of autophagy, the 18 kDa cytosolic LC3 (LC3B-I) undergoes proteolytic cleavage followed by a lipid modification and is converted to the 16 kDa membrane-bound form (LC3B-II), which is specifically localized to the autophagosomal membranes.
LC3 Binding (converted) of LC3B-II in cleavage
1) Confidence 0.19 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2950155 Disease Relevance 0.36 Pain Relevance 0

General Comments

This test has worked.

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