INT335738

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.88
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (VCP) endoplasmic reticulum (VCP) cytoplasm (VCP)
cytosol (VCP) lipid binding (VCP) cell death (VCP)
VCP (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 2 60.12 Quite High
Eae 10 5.00 Very Low Very Low Very Low
Hippocampus 8 5.00 Very Low Very Low Very Low
imagery 6 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 54 96.80 Very High Very High Very High
Respiratory Failure 2 96.72 Very High Very High Very High
Muscle Weakness 34 94.76 High High
Agraphia 2 92.04 High High
Dyslexia 2 91.48 High High
Apoptosis 48 90.12 High High
Anomia 2 83.36 Quite High
Frontotemporal Dementia 16 78.84 Quite High
Dementia 6 76.68 Quite High
Bone Disease 24 66.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Molecular genetic studies revealed that IBMPFD is caused by mutations in the Valosin Containing Protein (VCP) gene [7], and thus far 19 disease mutations have been identified (for review see [6], [14]).
Positive_regulation (caused) of IBMPFD associated with disease
1) Confidence 0.06 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2950155 Disease Relevance 1.32 Pain Relevance 0.06
Most of these mutated residues causing IBMPFD are three-dimensionally located in close proximity and potentially interact with each other [26].
Positive_regulation (causing) of IBMPFD
2) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2950155 Disease Relevance 0.56 Pain Relevance 0

General Comments

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