INT335848

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.25
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Lepr) extracellular space (Lepr) extracellular region (Lepr)
plasma membrane (Lepr)
Lepr (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 49 58.00 Quite High
cytokine 34 5.00 Very Low Very Low Very Low
agonist 7 5.00 Very Low Very Low Very Low
chemokine 6 5.00 Very Low Very Low Very Low
tolerance 6 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 125 100.00 Very High Very High Very High
Increased Venous Pressure Under Development 2 67.36 Quite High
Toxicity 5 61.04 Quite High
INFLAMMATION 49 58.00 Quite High
Stress 9 49.28 Quite Low
Weight Gain 2 40.20 Quite Low
Disease 2 33.80 Quite Low
Death 22 5.00 Very Low Very Low Very Low
Apoptosis 15 5.00 Very Low Very Low Very Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although we did not maintain our own colony of NOD mice, a colony kept by a collaborating laboratory (PLK) in the same animal suite has a spontaneous diabetes incidence of 80–90% in females by 30 weeks of age [56] indicating an animal environment that is conducive for diabetes development.


Positive_regulation (conducive) of Gene_expression (development) of diabetes associated with diabetes mellitus
1) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2950856 Disease Relevance 1.25 Pain Relevance 0.03

General Comments

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