INT335851

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.17
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il10) extracellular region (Il10) RNA binding (Snrpc)
intracellular (Il10) nucleus (Snrpc)
Snrpc (Mus musculus)
Il10 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 49 100.00 Very High Very High Very High
cytokine 34 100.00 Very High Very High Very High
tolerance 6 88.92 High High
agonist 7 5.00 Very Low Very Low Very Low
chemokine 6 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 125 100.00 Very High Very High Very High
INFLAMMATION 49 100.00 Very High Very High Very High
Death 22 91.92 High High
Disease Progression 1 81.24 Quite High
Apoptosis 15 68.84 Quite High
Autoimmune Disease 2 15.52 Low Low
Stress 9 9.28 Low Low
Toxicity 5 5.00 Very Low Very Low Very Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found that cSN50 inhibits pro-inflammatory cytokine expression in ex vivo analyzed NOD splenocytes while preserving and even modestly enhancing the anti-inflammatory cytokine IL-10.
cSN50 Positive_regulation (enhancing) of IL-10 associated with inflammation, diabetes mellitus and cytokine
1) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2950856 Disease Relevance 1.17 Pain Relevance 0.50

General Comments

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