INT335871

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Context Info
Confidence 0.18
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.91
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Sfrp2) extracellular space (Sfrp2) cell death (Sfrp2)
extracellular region (Sfrp2) plasma membrane (Sfrp2) cytoplasm (Sfrp2)
Anatomy Link Frequency
mammary gland 2
Sfrp2 (Mus musculus)
Pain Link Frequency Relevance Heat
Osteoarthritis 2 60.56 Quite High
antagonist 6 50.00 Quite Low
adenocard 2 32.80 Quite Low
midbrain 2 16.16 Low Low
Serotonin 14 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stomach Cancer 2 99.84 Very High Very High Very High
Cervical Cancer 2 99.36 Very High Very High Very High
Osteoarthritis 2 60.56 Quite High
Bone Cancer 12 60.40 Quite High
Multiple Myeloma 2 59.80 Quite High
Disease 14 58.80 Quite High
Osteoporosis 20 53.28 Quite High
Congenital Anomalies 8 16.88 Low Low
Embryonic Lethality 2 13.44 Low Low
Fracture Healing 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It should be noted, though, that down regulation of sFRP-1 predisposes the mammary gland to tumorigenesis [98] while sFRP-2 is significantly downregulated in gastric cancer [99], and downregulation of both sFRP-1 and sFRP-2 contributes to cervical cancer progression [100].
Negative_regulation (downregulated) of sFRP-2 in mammary gland associated with cervical cancer and stomach cancer
1) Confidence 0.18 Published 2010 Journal Journal of Osteoporosis Section Body Doc Link PMC2951123 Disease Relevance 0.43 Pain Relevance 0.03
It should be noted, though, that down regulation of sFRP-1 predisposes the mammary gland to tumorigenesis [98] while sFRP-2 is significantly downregulated in gastric cancer [99], and downregulation of both sFRP-1 and sFRP-2 contributes to cervical cancer progression [100].
Negative_regulation (downregulation) of sFRP-2 in mammary gland associated with cervical cancer and stomach cancer
2) Confidence 0.18 Published 2010 Journal Journal of Osteoporosis Section Body Doc Link PMC2951123 Disease Relevance 0.48 Pain Relevance 0.03

General Comments

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