INT335874

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Context Info
Confidence 0.18
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

anatomical structure development (Lrp4) plasma membrane (Lrp4)
Lrp4 (Mus musculus)
Pain Link Frequency Relevance Heat
Serotonin 7 98.14 Very High Very High Very High
antagonist 3 50.00 Quite Low
cINOD 2 5.00 Very Low Very Low Very Low
midbrain 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Osteoarthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Bone Cancer 6 37.92 Quite Low
Osteoporosis 10 36.96 Quite Low
Disease 7 5.00 Very Low Very Low Very Low
Fracture Healing 5 5.00 Very Low Very Low Very Low
Congenital Anomalies 4 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low
Syndrome 3 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Syndactyly 2 5.00 Very Low Very Low Very Low
Craniofacial Abnormalities 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
While not discounting the potential importance of serotonin-based therapies, this paper primarily focuses on the development of agents that potentially target LRP5, and the related proteins LRP6 and LRP4, in the bone itself.

2.

Regulation (target) of LRP4 associated with serotonin
1) Confidence 0.18 Published 2010 Journal Journal of Osteoporosis Section Body Doc Link PMC2951123 Disease Relevance 0 Pain Relevance 0.23

General Comments

This test has worked.

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