INT335891

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Context Info
Confidence 0.39
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.57
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Dkk1, Lrp5) mitochondrion (Lrp5) extracellular space (Dkk1)
extracellular region (Dkk1) endoplasmic reticulum (Lrp5)
Dkk1 (Mus musculus)
Lrp5 (Mus musculus)
Lrp5 - G171V (1)
Pain Link Frequency Relevance Heat
antagonist 3 50.00 Quite Low
Pain 1 15.12 Low Low
Serotonin 7 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
midbrain 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Osteoarthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Syndrome 3 93.84 High High
Retina Disease 1 91.24 High High
Osteoporosis 10 80.72 Quite High
Disease 7 72.64 Quite High
Pain 1 15.12 Low Low
Cancer 4 6.24 Low Low
Bone Cancer 6 5.00 Very Low Very Low Very Low
Fracture Healing 5 5.00 Very Low Very Low Very Low
Congenital Anomalies 4 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The LRP5-G171V protein can no longer be bound by several proteins (such as Dkk1, Sost, and MESD) that may normally regulate its activity.
Dkk1 Binding (bound) of LRP5 (G171V)
1) Confidence 0.39 Published 2010 Journal Journal of Osteoporosis Section Body Doc Link PMC2951123 Disease Relevance 0.57 Pain Relevance 0

General Comments

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