INT335991

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Context Info
Confidence 0.42
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.57
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Igfbp3) nucleus (Igfbp3)
Anatomy Link Frequency
cleavage 4
Igfbp3 (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 90 100.00 Very High Very High Very High
Inflammation 40 98.48 Very High Very High Very High
metalloproteinase 20 67.92 Quite High
Inflammatory response 18 56.48 Quite High
cytokine 34 20.64 Low Low
chemokine 8 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fibrosis 54 100.00 Very High Very High Very High
INFLAMMATION 58 98.48 Very High Very High Very High
Pulmonary Fibrosis 42 88.88 High High
Targeted Disruption 38 86.96 High High
Injury 20 65.32 Quite High
Disease 10 29.84 Quite Low
Lung Injury 4 23.28 Low Low
Autoimmune Disease 2 10.40 Low Low
Adult Respiratory Distress Syndrome 2 5.00 Very Low Very Low Very Low
Respiratory Failure 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recruited neutrophils release MMP-9, which has a protective role in bleomycin-induced fibrosis [17] through cleavage of potential profibrotic mediators such as insulin-like growth factor binding protein-3 (IGFBP3).
Positive_regulation (induced) of Localization (Recruited) of IGFBP3 in cleavage associated with fibrosis
1) Confidence 0.42 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2951918 Disease Relevance 0.79 Pain Relevance 0.31
Recruited neutrophils release MMP-9, which has a protective role in bleomycin-induced fibrosis [17] through cleavage of potential profibrotic mediators such as insulin-like growth factor binding protein-3 (IGFBP3).
Positive_regulation (induced) of Localization (Recruited) of factor binding protein-3 in cleavage associated with fibrosis
2) Confidence 0.36 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2951918 Disease Relevance 0.79 Pain Relevance 0.30

General Comments

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