INT336105

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Context Info
Confidence 0.39
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.63
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Slc2a4) transport (Slc2a4) transmembrane transporter activity (Slc2a4)
plasma membrane (Slc2a4) transmembrane transport (Slc2a4) cytoplasm (Slc2a4)
Anatomy Link Frequency
muscle tissue 1
soleus 1
Slc2a4 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 18 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 66 99.36 Very High Very High Very High
Insulin Resistance 21 84.48 Quite High
Obesity 33 79.80 Quite High
Weight Gain 12 36.80 Quite Low
Disorder Of Lipid Metabolism 33 9.84 Low Low
Body Weight 18 7.36 Low Low
Impaired Glucose Tolerance 18 5.00 Very Low Very Low Very Low
Hyperglycemia 9 5.00 Very Low Very Low Very Low
Hyperlipidemia 6 5.00 Very Low Very Low Very Low
Lipid Metabolism Disorders 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In muscle tissue, p38 MAPK takes part in the activation of GLUT4 [30, 32].
Positive_regulation (activation) of GLUT4 in muscle tissue
1) Confidence 0.39 Published 2011 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2952334 Disease Relevance 0.34 Pain Relevance 0
mg/kg) to STZ-diabetic rats for 3 days resulted in an increase in the mRNA and protein levels of the GLUT4 in soleus muscle, in addition to the lowering of plasma glucose [35].
Positive_regulation (increase) of GLUT4 in soleus associated with diabetes mellitus
2) Confidence 0.33 Published 2011 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2952334 Disease Relevance 0.15 Pain Relevance 0
Two groups also reported that berberine was able to stimulate GLUT4 translocation [10, 34], but this activity was not observed by other groups [10, 22].
Positive_regulation (stimulate) of GLUT4
3) Confidence 0.33 Published 2011 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2952334 Disease Relevance 0.14 Pain Relevance 0

General Comments

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