INT336123

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Context Info
Confidence 0.44
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.20
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.


Pain Term Frequency Confidence Heat
Bioavailability 2 72.32 Quite High
cytokine 1 5.00 Very Low Very Low Very Low
fibrosis 3 5.00 Very Low Very Low Very Low
withdrawal 3 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Term Frequency Confidence Heat
Diabetes Mellitus 23 99.64 Very High Very High Very High
Disease 2 98.64 Very High Very High Very High
Hypertension 34 50.00 Quite Low
Fibrosis 2 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low
Metabolic Syndrome 4 5.00 Very Low Very Low Very Low
Obesity 10 5.00 Very Low Very Low Very Low
Atherosclerotic Plaque 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pharmacokinetic studies have shown that there is no need for dose adjustment in patients with renal or hepatic disease or for elderly patients or patients with diabetes.11,12 Due to its lack of effect on cytochrome P450 isoenzyme activities, aliskiren has a low potential for drug interactions.9

Effects of aliskiren on RAS components

Regulation (lack) of Gene_expression (activities) of cytochrome P450 isoenzyme associated with diabetes mellitus and disease
1) Confidence 0.44 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2952455 Disease Relevance 0.20 Pain Relevance 0.04

General Comments

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