INT336335

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.68
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Mmp13) signal transducer activity (Glp2r) peptidase activity (Mmp13)
extracellular space (Mmp13) extracellular region (Mmp13) homeostatic process (Glp2r)
Glp2r (Rattus norvegicus)
Mmp13 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 10 99.96 Very High Very High Very High
metalloproteinase 4 83.48 Quite High
cytokine 27 70.76 Quite High
Inflammation 28 70.40 Quite High
Inflammatory response 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Buprenorphine 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 38 97.80 Very High Very High Very High
INFLAMMATION 31 70.40 Quite High
Wound Healing 11 65.44 Quite High
Injury 14 15.20 Low Low
Anastomotic Leak 4 5.00 Very Low Very Low Very Low
Stress 3 5.00 Very Low Very Low Very Low
Inflammatory Bowel Disease 2 5.00 Very Low Very Low Very Low
Exsanguination 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Adhesions 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There were no major effects on MMP-13 mRNA levels by the GLP-2 agonists, under either ambient oxygen status; however, there were interesting statistically significant increases in mRNA levels for TIMP 1, 2, and 3 in hypoxic animals treated with GLP-2-MMB, but not native GLP-2 (data not shown).


GLP-2 Neg (no) Regulation (effects) of MMP-13 mRNA associated with hypoxia and agonist
1) Confidence 0.06 Published 2010 Journal Gastroenterology Research and Practice Section Body Doc Link PMC2952794 Disease Relevance 0.68 Pain Relevance 0.28

General Comments

This test has worked.

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