INT336458

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 6
Disease Relevance 2.92
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transferase activity, transferring glycosyl groups (MGAT1) Golgi apparatus (MGAT1) carbohydrate metabolic process (MGAT1)
Anatomy Link Frequency
bowel 1
MGAT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 30 99.20 Very High Very High Very High
rheumatoid arthritis 6 82.92 Quite High
Osteoarthritis 12 82.04 Quite High
Piles 6 68.80 Quite High
Pain 6 62.56 Quite High
fibrosis 6 49.12 Quite Low
psoriasis 6 34.08 Quite Low
Disease Link Frequency Relevance Heat
Injury 12 99.28 Very High Very High Very High
Inflammatory Bowel Disease 36 99.20 Very High Very High Very High
Wrinkles 18 91.52 High High
Shock 12 89.76 High High
Osteoarthritis 24 85.64 High High
Rheumatoid Arthritis 6 82.92 Quite High
Metastasis 18 81.80 Quite High
Disease 42 81.40 Quite High
Cancer 12 81.36 Quite High
Arthritis 6 81.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The major repeating disaccharide unit of keratin sulfate, also called keratosulfate, is composed of galactose and sulfated GlcNAc.
Positive_regulation (sulfated) of GlcNAc
1) Confidence 0.05 Published 2010 Journal Marine Drugs Section Body Doc Link PMC2953398 Disease Relevance 0.35 Pain Relevance 0.03
GlcNAc is used as a substrate in sialic acid production
Positive_regulation (used) of GlcNAc
2) Confidence 0.05 Published 2010 Journal Marine Drugs Section Body Doc Link PMC2953398 Disease Relevance 0.53 Pain Relevance 0.06
In fact, GlcNAc and sulfated GlcNAc can be isolated from heparin or keratin sulfate [25,26].
Positive_regulation (sulfated) of GlcNAc
3) Confidence 0.05 Published 2010 Journal Marine Drugs Section Body Doc Link PMC2953398 Disease Relevance 0.38 Pain Relevance 0.04
GlcNAc is a potential candidate to treat inflammatory bowel disease (IBD)
Positive_regulation (potential) of GlcNAc in bowel associated with inflammatory bowel disease and inflammation
4) Confidence 0.05 Published 2010 Journal Marine Drugs Section Body Doc Link PMC2953398 Disease Relevance 1.58 Pain Relevance 0.26
In this process, a high concentration (exceeding 120 g/L) of GlcNAc was obtained after fermentation for 60 h and is, thus, the most efficient process by far.


Positive_regulation (concentration) of GlcNAc
5) Confidence 0.05 Published 2010 Journal Marine Drugs Section Body Doc Link PMC2953398 Disease Relevance 0.07 Pain Relevance 0
Further purification procedures are necessary to recover GlcNAc from the filtrate.
Positive_regulation (recover) of GlcNAc
6) Confidence 0.05 Published 2010 Journal Marine Drugs Section Body Doc Link PMC2953398 Disease Relevance 0 Pain Relevance 0

General Comments

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