INT336491

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Context Info
Confidence 0.49
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.46
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
superior 2
IFN1@ (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 38 100.00 Very High Very High Very High
Inflammation 29 100.00 Very High Very High Very High
Gabapentin 1 47.40 Quite Low
Inflammatory response 8 21.92 Low Low
Inflammatory mediators 5 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 42 100.00 Very High Very High Very High
Syndrome 124 99.64 Very High Very High Very High
Infection 73 94.48 High High
Cerebral Malaria 2 93.68 High High
Generaliased Trisomy 1 91.28 High High
Disease 38 87.12 High High
Renal Cancer 63 83.60 Quite High
Toxicity 28 81.64 Quite High
American Trypanosomiasis 23 80.00 Quite High
Coronary Heart Disease 3 75.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The modulatory effect of the coinfection was abolished in IL-10-deficient mice clearly showing the central role of IL-10 in inhibiting the inflammatory cytokines IFN-?
Positive_regulation (role) of Negative_regulation (inhibiting) of IFN associated with inflammation and cytokine
1) Confidence 0.49 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2953483 Disease Relevance 1.02 Pain Relevance 0.21
in DS are likely to be related to the presence of several IFN receptor genes in chromosome 21 including IFNGR2, which is one of the subunits of the IFN-?
Positive_regulation (related) of Negative_regulation (presence) of IFN associated with syndrome
2) Confidence 0.49 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2996288 Disease Relevance 1.05 Pain Relevance 0.05
Indirect comparison suggested sunitinib was superior to bevacizumab plus IFN-?
Positive_regulation (superior) of Negative_regulation (bevacizumab) of IFN in superior
3) Confidence 0.49 Published 2010 Journal Cancer management and research Section Body Doc Link PMC3004565 Disease Relevance 0.38 Pain Relevance 0

General Comments

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