INT336557

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Context Info
Confidence 0.08
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.50
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (SLC6A3, GOPC) cytoplasm (SLC6A3, GOPC) transport (SLC6A3)
cell death (SLC6A3) aging (SLC6A3) Golgi apparatus (GOPC)
Anatomy Link Frequency
neurons 4
SLC6A3 (Homo sapiens)
GOPC (Homo sapiens)
Pain Link Frequency Relevance Heat
Dopamine 130 92.64 High High
Spinal cord 88 91.04 High High
monoamine 6 78.48 Quite High
Dorsal horn 10 74.00 Quite High
Locus ceruleus 6 34.80 Quite Low
Pain 14 5.00 Very Low Very Low Very Low
Migraine 10 5.00 Very Low Very Low Very Low
spinal dorsal horn 4 5.00 Very Low Very Low Very Low
Dorsal column 4 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Parkinson's Disease 72 94.56 High High
Disease 14 85.52 High High
Poisoning 20 26.64 Quite Low
Restless Legs Syndrome 20 5.00 Very Low Very Low Very Low
Pain 12 5.00 Very Low Very Low Very Low
Headache 10 5.00 Very Low Very Low Very Low
Sleep Disorders 6 5.00 Very Low Very Low Very Low
Nociception 4 5.00 Very Low Very Low Very Low
Overdose 2 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The absence of DAT expression was not due to a lack of specificity of the techniques used since SN neurons serving as positive control were clearly positive for DAT-IR (Fig. 8A), DAT binding (Fig. 8D) and DAT mRNA expression (Fig. 8G).


DAT-IR Positive_regulation (positive) of Fig Binding (binding) of in neurons
1) Confidence 0.08 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2954154 Disease Relevance 0.25 Pain Relevance 0.29
The absence of DAT expression was not due to a lack of specificity of the techniques used since SN neurons serving as positive control were clearly positive for DAT-IR (Fig. 8A), DAT binding (Fig. 8D) and DAT mRNA expression (Fig. 8G).


DAT Positive_regulation (positive) of Fig Binding (binding) of in neurons
2) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2954154 Disease Relevance 0.25 Pain Relevance 0.29

General Comments

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